The adenosinergic system, principally mediated by four subtypes of G-protein-coupled adenosine receptors (A1, A2A, A2B and A3), plays a pivotal role in the regulation of immune responses.

A 1 AR Brain (cortex, hippocampus, cerebellum), spinal cord, eye, adrenal gland, atria, liver, kidney, adipose tissue, salivary glands, esophagus, colon, atrium and ...

A recent study by researchers at the University of Florence and collaborators has demonstrated the efficacy of MRS-3997, a dual adenosine A2A/A2B receptor agonist, in reducing brain damage and ...

Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...

This article is based on a poster originally authored by Philip Rawlins, Jim Reid, William Lee, Holly Madden, Soumya Dhanavade, James Craswell, Satya Bhamidimarri, Anna Hopkins, Joe Mason, Marieke ...

WESTPORT, Conn., Jan. 06, 2025 (GLOBE NEWSWIRE) -- Portage Biotech, Inc. (“Portage” or the “Company”) (NASDAQ: PRTG), a clinical-stage immuno-oncology company with a portfolio of innovative ...

For many people, morning is impossible to navigate without at least one cup of coffee. Amidst its many compounds that give this brew its unique taste, coffee contains caffeine, which helps push away ...