Aldosterone antagonists (spironolactone ... with recent or current New York Heart Association functional class IV symptoms, preserved renal function and a normal potassium concentration.

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Aldosterone Receptor Blockers ... on survival in severely symptomatic (New York Heart Association class IV) heart failure patients taking an ACE inhibitor, loop diuretic, and digoxin.