I present the evidence that renal dysfunction is a common and powerful cardiovascular risk factor and that treatment strategies intervening in the renin–angiotensin–aldosterone system can be ...

The first recipient of a gene-edited pig kidney died from cardiac causes 52 days after xenotransplantation. The world's first recipient of a gene-edited pig kidney died from cardiac causes within 2 ...

The following is a summary of “Treating chronic kidney disease in Danish primary care: results from the observational ATLAS study,” published in the February 2025 issue of BMC Primary Care by ...

High blood pressure affects one in three adults, of whom a hormonal condition called primary aldosteronism accounts for one ...

Jiangsu Hansoh Pharmaceutical Group Co. Ltd. and Shanghai Hansoh Biomedical Co. Ltd. have divulged cytochrome P450 11B2, mitochondrial (CYP11B2; aldosterone synthase; ALDOS) inhibitors reported to be ...

The body retains more water and salt when kidney function declines, leading to Edema in the extremities. The hormonal axis ...

Pathophysiology of hepatorenal syndrome-acute kidney injury ... including the renin–angiotensin–aldosterone system, sympathetic nervous system, and arginine vasopressin, are activated to ...

Baxdrostat is a drug that reduces aldosterone levels in the body to treat high blood pressure and other conditions. It's an aldosterone synthase inhibitor (ASI) that's being studied as a treatment for ...