Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...

"Knowing the genetic identity and location of neurons that control this ... Ph.D., made their discovery by teasing out the actions of aldosterone, a key hormone for controlling sodium levels.