Please provide your email address to receive an email when new articles are posted on . There are several challenges to implementing the live-attenuated, temperature-sensitive influenza vaccine ...

A promising strategy to reduce the impact of viral infectious diseases, such as influenza, is the use of attenuated, live viruses as vaccines. However, the usefulness of traditional live-attenuated ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causal agent of the coronavirus disease 2019 (COVID-19), has a polybasic cleavage motif in the spike (S) protein. This is ...

EV25 was generally well-tolerated and demonstrated a good safety profile, with no observable dose-dependent safety trends.

Live-attenuated influenza vaccine (LAIV), administered intranasally, is unlikely to trigger systemic allergic reactions in children (aged 2 - 18 years) with egg allergy and is well tolerated in those ...

The efficacy of influenza vaccines may decline during years when the circulating viruses have antigenically drifted from those included in the vaccine. A total of 1247 persons were vaccinated between ...

Reviews of Infectious Diseases, Vol. 5, No. 3, 1982 International Symposium on Measles Immunization (May - Jun., 1983), pp. 477-481 (5 pages) Further-attenuated strains of measles virus may be ...

Use the tissue culture to grow new viruses. You are about to create a live-attenuated vaccine, which means that you need to alter a pathogen—in this case a measles virus—so that it will still invade ...

Since the beginning of the COVID-19 pandemic, researchers have been working on mucosal vaccines that can be administered through the nose. Now, scientists in Berlin have developed a live attenuated ...

Jeryl-Lynn strain (B level) live, attenuated mumps-virus vaccine was administered to 6283 initially susceptible children and 163 adults, including 132 males. There was no evident clinical reaction to ...