Use the tissue culture to grow new viruses. You are about to create a live-attenuated vaccine, which means that you need to alter a pathogen—in this case a measles virus—so that it will still ...

Live attenuated vaccines are antigenic substances composed of a viable (living) pathogen, such as a virus or bacterium. The pathogen is altered so that it is less virulent or avirulent (attenuated).

The tumor microenvironment plays a crucial role in the resistance of solid tumors to immunotherapy. In particular, fibroblast activation protein (FAP)-expressing cancer-associated fibroblasts have ...

Live-attenuated viral vaccines (LAV) have been used safely for several decades in healthy individuals to protect against diseases with great success. In immunocompromised hosts their use is ...

The novel live-attenuated SARS-CoV-2 nasal vaccine candidate is highly safe, induces robust cellular and mucosal immunity, and generates long-lasting neutralizing antibody titers.