SMAD5 expression and inhibition of the mitotic kinase aurora-A on sensitivity of breast cancer cells to chemotherapy. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This ...

Illustration showing how autophagy induction increases the efficiency of precise gene editing. In normal cells, DNA breaks caused by CRISPR–Cas9 are frequently repaired through non-homologous end ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

Autophagy is a natural process that occurs as your body clears out and replaces damaged cell parts with new ones. It occurs within your body at all times. It has been linked to a long list of ...