A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Neurodegeneration in brain cells may be happening when the natural cellular cleaning process malfunctions due to falling levels of a niacin-related coenzyme and leaves cells starved of energy, new ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Scientists from Brown University say they have demonstrated a novel method for stimulating autophagy. In a study (“Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan”), ...

Recent studies suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), like other coronaviruses, hijacks various host cell machinery such as autophagy for replication and ...

A new study sheds light on how autophagy, the body’s process for removing damaged cell parts, when impaired, can play a role in causing heart failure. The research team led by Dr. E. Dale Abel, chair ...

In Japan, cancer has been the leading cause of death since 1981. At present, surgery, chemotherapy, and radiotherapy are the main treatment options. However, these treatments considerably reduce ...

Phenotypic differences in tumor-associated macrophages between metastatic and primary sites of clear cell renal cell carcinoma. This is an ASCO Meeting Abstract from the 2018 ASCO-SITC Clinical Immuno ...

Investigators at Sanford Burnham Prebys Medical Discovery Institute (SBP) say they have begun the first analysis of autophagy in a living animal as it ages. Autophagy is the normal physiological ...

Chemotherapies treat cancer by killing tumor cells, but certain types of chemotherapy can also drive an immune system response to target and destroy the remaining tumor cells. This immune targeting is ...