We also determined which CD4 + T cell population is critical for induction of negative regulation of CTL tumor immunosurveillance, and found it was dependent on CD1-restricted NKT cells.

We have developed a non-radioactive flow-cytometry assay to monitor and quantify the target-cell killing activities mediated by cytotoxic T lymphocytes (CTLs). This flow-cytometry CTL (FCC ...

But others, often when they’re infected with viruses, opt for a messier, more violent form: necroptosis, which harnesses the immune system to attack and kill the body’s own cells. In recent years, ...

Effective immune responses against infectious agents and cancer require that immune cells traffic ... how specific aspects of synaptic architecture promote target cell killing. Our approach relies ...

10, 2025) – A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor ...

Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice. The novel drug CT-179 ...