the CXC chemokine ligand–receptor pair CXCL12–CXCR4, as well as interactions involving Wnt signaling. The bone marrow microenvironment also provides survival niches for antibody-secreting ...

The stromal-derived factor-1 (SDF-1)/CXCR4 axis is a major determinant in the crosstalk between leukemic cells and BM stroma. In this study, we investigated the use of AMD11070, an orally ...

Elevated expression of C-X-C motif chemokine ligand 12 (CXCL12) and C-X-C motif chemokine receptor 4 (CXCR4) in the plasma or atria in patients with AF has been linked to increased atrial ...

Our previous reports have focused on the tumor microenvironment in liver cancer, including the role of CXCR4, a receptor for CXCL12, which helps weaken the immune system's ability to fight cancer ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...