A new area of cancer immunotherapy is enhancing therapeutic mAb-mediated CD16 activation of NK cells. CAR-NK cells containing multi-specific molecules made up of relatively stable CD16 and other ...

2024年8月，国际知名学术期刊《Cureus》上发表的一项临床病例报告，详细记录了一位61岁晚期肝细胞癌患者在接受联合NK细胞治疗方案（DC疫苗+NK细胞+纳武利尤单抗）后，病情得到显著改善。其中，肝脏储备功能显著改善，肝部肿瘤体积大幅减小，为后续 ...

Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using ...

为解决 HIV 无法治愈难题，西班牙巴塞罗那瓦尔德希伯伦大学医院等单位研究人员开展 Bi-Ab32/16 抗体研究。结果显示其体外有效，体内却导致 NK 细胞减少影响病毒控制。该研究为 HIV 免疫疗法提供关键线索，强烈推荐科研人员阅读。

Human NK cells are a subset of peripheral blood lymphocytes defined by the expression of CD56 or CD16 and the absence of the T-cell receptor CD3. NK cells comprise of 10–15% of the lymphocyte ...

For expression of CD3, CD56, NKG2D, NKp46 and CD16, non-expanded PB mononuclear cells (PBMCs) and corresponding ex vivo expanded NK cells were washed, treated with human FcR blocking reagent (BD ...

Immunotherapy. 2011;3(9):1075-1086. MIP-1β release has also been observed for CD56 neg NK cells from patients with HCV infection. The above results suggest that the aberrant CD56 neg NK subset ...

SAR443579 (also known as IPH6101) is a tri-functional NKp46/CD16-based anti-CD123 NK cell engager – described as a first-in-class therapy – that has now advanced into a phase 2 programme.

NK cells are a crucial component of the innate ... These cells are characterized by their expression of CD56 and CD16 and can ...