Using DNA microarray–derived gene expression data from complex tissues and the relative frequencies of cell types in the tissue as input the algorithm csSAM finds cell type–specific ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

Nature Genetics - Clustering cell types and identifying cell-type specific transcripts by gene expression profiling in single neurons Skip to main content Thank you for visiting nature.com.

The Hirohide Saito Laboratory has developed cyclic RNA switches that can control gene expression in a cell type-specific manner using miRNAs and RNA-binding proteins and has successfully ...

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that ...

Gene-Expression and Immunohistochemical Study of Specific T-Cell Subsets and Accessory Cell Types in the Transformation and Prognosis of Follicular Lymphoma. JCO 25 , 390-398 (2007). DOI: ...

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that ...

More information: Dennis Joshy et al, Accelerated cell-type-specific regulatory evolution of the human brain, Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2411918121 ...

“A critical observation of this study is that cell type-specific aging patterns in cells can be used to gauge biological age, that is the relative aging status of an organism, independent of its ...

Gene expression in the human brain: cell types become more specialized, not just more numerous. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 01 ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...