In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

Viral infections remain a significant global health challenge, as exemplified by recent pandemics. The complexity of virus-host interplay poses major ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how an innovative and stable mRNA-LNP microneedle vaccine elicits humoral and multifunctional cellular immune responses.

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Hai-Hui "Howard" Xue, Ph.D., of the Hackensack Meridian Center for Discovery and Innovation (CDI) have shown how a critical pathway is fundamental to the immune system, in a new papers in the journal ...

Explore the evolution of T-cell engagers, from experimental concepts to effective therapies for haematologic malignancies.

It is generally agreed that a number of types of nutritional deficiencies, including vitamin D-deficient rickets, can cause a temporary state of immune deficiency. As a result, children with rickets ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...

A researcher at the Hackensack Meridian Center for Discovery and Innovation (CDI) and physician-scientist colleagues from Hackensack Meridian Health have shown how a critical pathway is fundamental to ...

New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the ...