撰文丨王聪编辑丨王多鱼排版丨水成文衰老(Aging)的主要特征表现为器官及生物体生理完整性与功能的逐步丧失。它也是衰老相关疾病的首要风险因素。最新研究进一步证实,细胞衰老(Cellular Senescence)是机体衰老(Organismal ...
撰文丨王聪编辑丨王多鱼排版丨水成文细胞衰老(Cellular senescence)通常被定义为一种细胞状态,其特征是在没有细胞死亡的情况下细胞周期永久性停滞。衰老细胞表现出几个典型的特征,包括停止分裂状态、细胞形态改变、线粒体功能障碍、活性氧(ROS)水平升高、DNA ...
This Collection supports and amplifies research related to SDG 3. This is a joint Collection across npj Aging, Nature Aging, Nature Metabolism, Nature Cell Biology and Scientific Reports. Please see ...
Our work highlights the need to study polyploidy and senescence in concert to understand their roles in aging, cancer, and ...
Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...
Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...
Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...
A new meeting report was published in Volume 17, Issue 12 of Aging-US on December 23, 2025, titled "Cellular senescence meets infection: highlights from the 10th annual International Cell Senescence ...
Explore the risks of postpartum cancer and discover how cellular senescence affects breast tissue after pregnancy.
Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively ...
Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant ...