Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase, an enzyme that catalyzes the conversion of HMG-CoA into mevalonate, proved to be the rate-controlling enzyme in cholesterol synthesis. On the basis ...

SINCE the demonstration that squalene might be an important precursor to cholesterol in endogenous synthesis 1–3, it was felt that it would be useful to have available an adequate supply of ...

Following digestion and absorption of dietary fat, TG and cholesterol are packaged to form chylomicrons in the epithelial cells of the intestines. Chylomicrons circulate through the intestinal ...

HDLs are high-density lipoproteins. The role of HDL is to transport excess cholesterol from the rest of the body to the liver for elimination from the body. LDLs are low-density lipoproteins.

Statin, which prevents the synthesis of cholesterol and lowers bad LDL cholesterol in the blood, is used for medicines for hyperlipidemia, a disease linked to cerebral and cardiac infarction.