Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

Commonly used prescription medications have a post-lanosterol biosynthesis inhibiting effect. Pathogenic variants in the DHCR7 gene result in SLOS ...

Following digestion and absorption of dietary fat, TG and cholesterol are packaged to form chylomicrons in the epithelial cells of the intestines. Chylomicrons circulate through the intestinal ...

Cholesterol has many myths which often mislead people about their health. Cholesterol is essential for the body, and ...

they found that the astrocytes produced more of an enzyme that controls cholesterol synthesis. A similar occurrence had also been observed in a different group’s study, which looked at sequenced cell ...

SINCE the demonstration that squalene might be an important precursor to cholesterol in endogenous synthesis 1–3, it was felt that it would be useful to have available an adequate supply of ...

Statin, which prevents the synthesis of cholesterol and lowers bad LDL cholesterol in the blood, is used for medicines for hyperlipidemia, a disease linked to cerebral and cardiac infarction.