Find patient medical information for Digoxin on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings ...

The median exposure for digoxin was 480 DDDs (interquartile range 100–1400 DDDs). During a median follow-up of 7.5 years after diagnosis, 617 men (48 digoxin users) died of prostate cancer.

To investigate the effects of phorbol 12-myristate 13-acetate (PMA), a PKC activator, on P-glycoprotein-mediated efflux of digoxin in two cell transport models. Caco-2 cells, wild MDCKII cells ...

Digoxin could also mediate an increased risk directly through its effect on the Na-K pump. This pump is involved in transport of ions, such as Ca 2+, but it also is important in the transport of ...

This included 6712 who did not use digoxin and 2159 who did (high dose, n=1202; low dose, n=957). In the digoxin group, 618 members were transient users of the medication and 1541 were long-term ...

Digoxin therapy was not associated with a significantly increased rate of death among men (35.2 percent in the digoxin group, as compared with 36.9 percent in the placebo group; absolute ...

Digoxin is "usually a second-line option due to neutral mortality effects" in randomized clinical trials of patients with heart failure, reduced left ventricular ejection fraction and sinus rhythm ...

Digoxin's effect on the heart's rhythm and pumping ability may be implicated in the mechanisms that also can lead to death, particularly if levels of the drug in the blood go above the recognised ...

Digoxin-Dronedarone Interaction Investigated. Diana Ernst, RPh | December 16, 2014 . Getting to the Heart of the Matter: A Review of Potential Drug Interactions With Cardiac Medications ...

Digoxin takes two years to produce because the foxglove plant must fully mature before the leaves are harvested. “Then the leaves will dry for another year,” Wang explains, and after that, “the active ...