马来酸贝西福韦酯（besifovir dipivoxil maleate）是贝西福韦的前体药，口服可迅速被胃肠道吸收，原药及其代谢产物主要通过肾脏排泄[2]。

Adefovir dipivoxil, a nucleotide analogue, demonstrated clinically significant antiviral activity in patients with chronic hepatitis B in phase 1 and 2 clinical trials.We randomly assigned 185 pati ...

Adefovir dipivoxil (Hepsera, Gilead Sciences) is an oral prodrug of adefovir, an analogue of adenosine monophosphate. The active intracellular metabolite, adefovir diphosphate, inhibits HBV DNA ...

Studies have demonstrated the superior efficacy of adding adefovir dipivoxil to existing lamivudine therapy compared with switching to adefovir dipivoxil monotherapy in patients with lamivudine ...

To improve the oral absorption of adefovir dipivoxil (ADV) by employing MCT and the esterase inhibitor ethyl oleate (EO) as a complex oil phase in emulsion. EO was used as the esterase inhibitor ...

Laura Gater. May 20, 2005 (Chicago) — Treatment with 10 mg of adefovir dipivoxil for 192 weeks resulted in significant and sustained reductions in hepatitis B virus (HBV) DNA levels, with the ...

adefovir dipivoxil, compared with lamivudine then adefovir dipivoxil) – ICER $91,000 (£52,000) per QALY. 4.2.13 In the analysis for HBeAg-negative disease, lamivudine then adefovir dipivoxil (as ...

Feb. 26, 2003 -- Adefovir dipivoxil is effective for the treatment of hepatitis B, according to the results of two studies in the Feb. 27 issue of the New England Journal of Medicine. Neither ...

Peginterferon alfa-2a . 4.1.1 The Assessment Group found three randomised controlled trials investigating peginterferon alfa-2a in chronic hepatitis B. Two trials were in people with HBeAg-positive ...

Drug Name : Adefovir Dipivoxil Adefovir Dipivoxil is an antiviral agent prescribed to treat hepatitis B, a chronic viral infection of the liver in patients 12 years and above.