The supplement industry is booming—but so are serious health issues tied to taking these pills and powders. Here’s what ...

The liver is the major site of drug metabolism. Approximately 60 percent of marketed drugs are metabolized by hepatic CYP450s. Human liver microsomes (HLM) are an important in vitro experimental model ...

Drug-induced liver injury (DILI) is common because it can be caused ... understanding of the mechanisms that contribute to DILI and how advances in reactive metabolism trapping have improved detection ...

Scientists at Michigan Medicine have made a significant breakthrough in treating nonalcoholic fatty liver disease (NAFLD), a condition that affects billions worldwide. Their research has led to the ...

Next, Shulman and his team want to use their method to test the effects of these and other metabolism-related drugs on liver ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools ... In addition to analyzing biological fluids or tissues, we assay stability in liver microsomes and perform reaction ...

Mirum Pharmaceuticals' Ctexli wins FDA approval for CTX, a rare lipid storage disease. The company projects 2025 global sales of $420–$435 million.

Scientists from the University of California Davis have found that ibuprofen, a widely used painkiller, may have a bigger impact on the liver than previously thought. Their research also uncovered ...

Most drugs are metabolized by CYP3A enzymes, and variations in expression levels of these enzymes are believed to determine whether patients will have a positive or adverse drug response.

Jan 27 (Reuters) - Akero Therapeutics (AKRO.O), opens new tab shares gained 117% in early trading on Monday, after its lead drug showed it can help patients with a type of liver disease to reverse ...

GLP-1s are relatively new drugs, and liver disease is a slowly progressive ... “That doesn’t do anything for the fat accumulation and metabolism and obesity but can address the fibrosis ...