To understand the organization of the utrophin complex at neuromuscular junctions ... this connection because other syntrophin-associated proteins (dystrophin and utrophin) were less stringently ...

influencing the stability of the dystrophin-associated protein complex across tissues, a key indication of DMD. These findings offer a molecular explanation for the wide-ranging symptoms ...

Solid Biosciences (SLDB) announced initial data from the Phase 1/2 INSPIRE DUCHENNE trial evaluating SGT-003, a next-generation gene therapy ...

Dystrophin and DGC are also lost in Duchenne muscular dystrophy. The loss of dystrophin and damage to the DGC appear to be key players in the development of both cancer wasting and muscular dystrophy.