The failure of malignant cells to undergo apoptosis is a major obstacle in cancer therapy, and thus identifying the underlining molecules involved therein is imperative for improving patient survival.

The extracellular matrix (ECM) is a dynamic, heterogeneous scaffold known to regulate many aspects of cellular behaviour, such as cell shape, cell migration, stem-cell differentiation, and cell–cell ...

Focal adhesions and hemidesmosomes as integrin-dependent junctions for cell-matrix adhesion There are two types of integrin-dependent junctions where cell-matrix adhesion occurs. The first are called ...