Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM). An interlinked net of proteins and sugars that surrounds brain cells, the ...

Researchers show how damaged tissue is reshaped to trigger painful bone formation in muscles and tendons CHINA, ...

In a study published in Cell Stem Cell, researchers led by Profs. DAI Jianwu and ZHAO Yannan from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have ...

Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process. But the mechanical signals that guide tissue and organ ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...