Discovered over a decade ago, ferroptosis is a form of non-apoptotic cell death that depends on the production of reactive oxygen species (ROS), iron and lipid peroxidation. Ferroptosis has been a ...

A precursor of cholesterol, previously categorized as harmful, can protect cancer cells from cell death. In a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann Angeli has ...

第五届单细胞与空间组学论坛近日，南京医科大学第一附属医院研究团队在期刊《Advanced Science》上发表了研究论文，题为“KMT2C Loss Promotes NF2-Wildtype Meningioma Progression and ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive ...

Timeline diagram depicting essential discoveries in the field of ferroptosis research. The exploration of ferroptosis originated from the identification of system xc-, which was initially reported in ...

Iron metabolism imbalance and ferroptosis are central to PF pathogenesis, offering new therapeutic targets. Ferroptosis links oxidative stress, iron overload, and fibrotic remodeling, affecting key ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive ...

In a recent review published in the Cell Death Discovery Journal, researchers explored the association between ferroptosis and male reproductive failure, emphasizing the need for tailored therapies ...

Circulating kidney injury molecule-1 (KIM-1) in association with kidney injury biomarkers and outcomes in metastatic renal cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...

For the first time, researchers have identified a previously unrecognized metabolic defense mechanism in aggressive brain ...

Immunometabolism has emerged as a central hub linking infection, inflammation, cell death, and cancer. The metabolic state of cells profoundly shapes their ...