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Although for liver fibrogenesis not yet proven, subgroups of monocytes can differentiate into fibroblast-like cells (fibrocytes) after entering the damaged tissue.
The initial event that induces fibrogenesis in alcoholic chronic pancreatitis is the necrosis of fat tissue and the resorption of damaged cells by macrophages.
Fibrogenesis initiates in conjunction with ADM. (a – c) At the earliest stages of ADM, evidenced by small, irregular lumina lined by cells of both acinar and ductal morphologies (arrows ...
Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as ...
In a recent study published in Nature Metabolism, researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis. Fibrogenesis is a defensive reaction to ...
Special Article Archive Some Biochemical Aspects of Fibrogenesis and Wound Healing Author: David S. Jackson, Ph.D. Author Info & Affiliations Published October 23, 1958 N Engl J Med 1958;259: 814 ...
Taken together, studies on fibrogenesis in the liver (and other organs as well) are now pushed forward a lot, hopefully resulting in new impulses for therapy and diagnosis.