A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called ...

A visual depiction of a frameshift mutation. What is a duplication mutation? In the case of a duplication mutation, a piece of DNA is (abnormally) copied. This might happen once or several times, and ...

The frameshift mutation results in a premature stop codon (I390fs404X) that predicts a truncated protein of 404 amino acids, with a terminal sequence of 15 amino acids bearing no homology to the ...

In a paper published on aBIOTECH, the authors obtained viable knockout mutants with developmental defects by introducing frameshift mutations to C -terminus sequence of three essential protein kinase ...

This mutation causes a reading frameshift starting from residue Cys989, with the new reading frame ending with a premature stop codon two codons downstream, NM_017780.3(CHD7_i001):p.(Cys989Serfs*3).

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants. News-Medical, viewed 05 December 2024, https: ...

Identification of a novel frameshift mutation in the SCNN1B causing Liddle syndrome. Science China Press. Journal Science Bulletin DOI 10.1016/j.scib.2023.02.006. Keywords / Life sciences ...

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not ...

It demonstrated impressive neoantigen-specific T cell responses in all evaluable participants, inducing durable and robust immune responses against frameshift peptide neoantigens. Lynch Syndrome is ...

DNA mismatch repair deficiency causes insertion or deletion mutations at coding microsatellites, which leads to the generation of frameshift peptide (FSP) antigens. FSP antigens are attractive targets ...