Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

Ribosomes, the cell's protein-making factories, consume large amounts of energy as they build the proteins that keep cells ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

< 3D model of two rat hippocampal ribosomes interacting in a hibernating dimer via an RNA expansion se ... Copyright: Max Planck Institute for Brain Research, 3D models: Oliver Döll.

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer’s and Parkinson’s diseases, are caused by protein aggregation, a ...

Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...