This includes transcription, biogenesis ... to both mitotic and meiotic cell divisions. The classical epigenetic mechanisms include DNA methylation and histone modifications, but other mechanisms ...

Epigenetics is the study of various heritable alterations that control ... One function of histone modifications is to make DNA more or less accessible for transcription. Heterochromatin is highly ...

Scientists have identified an epigenetic mechanism that seems to balance gene expression. One facet of the mechanism can promote the transcription and organization of genes, while the other causes ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

During transcription, the DNA sequence of a gene is copied into a complementary RNA molecule called messenger RNA (mRNA). This process is carried out by the enzyme RNA polymerase, which binds to the ...

A multinational team has identified PfSnf2L, a key epigenetic regulator in Plasmodium falciparum, the deadliest malaria ...

Aging cells with weakened gene regulation spuriously transcribe RNAs ... normally seen at the start sites of transcription at sequences known as promoters and provides further support that epigenetic ...

May 9, 2024 — A recent study led to the development of a powerful epigenetic editing technology ... are reflected at the molecular level of gene activation (epigenome) in ...

We are multidisciplinary lab that combines computational biology, machine learning, AI and molecular biology to decode the contribution of epigenetics (DNA methylation and histone modifications), ...

New research about how smoking damages DNA could open new possibilities for targeted cancer prevention.Israeli and US ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...