Chemicals used in different applications induce genetic and epigenetic aberrations implicated in various diseases, including cancer. Researchers from Japan have developed a cell-based reporter assay ...

Integration of GenEvolutioN’s Best-in-Class Micronucleus Genotoxicity screen strengthens 3RnD as a unified digital ...

Gentronix entered into a three-year agreement to provide GlaxoSmithKline (GSK) with GreenScreen HC and BlueScreen HC genotoxicity assays. The reporter-based assays have demonstrated the ability to ...

The toxicological testing market is no stranger to the principle of the three Rs of research: replacement, reduction, and refinement. With that to guide us, we will review ways to fulfill these ...

While moderate sun exposure benefits health, excessive ultraviolet (UV) radiation can lead to sunburn, photoaging and long-term risks like skin cancer. Triazine-based UV filters, including ethylhexyl ...

Integration of the Xenometrix Ames mutagenicity test modernizes this cornerstone, regulatory-aligned NAM within the ...

AVROBIO, Inc. (Nasdaq: AVRO), a leading clinical-stage gene therapy company working to free people from a lifetime of genetic disease, today reported favorable data on the combined use of two state-of ...

The BlueScreen HC assay utilizes a luciferase from the marine copepod Gaussia princeps to generate a luminescent output. Exposure to a genotoxic chemical causes increased expression of GADD45a and ...

Pharmas and biotechs struggle to screen large quantities of compounds, hoping to eliminate early those that would prove more destructive than beneficial. One avenue toward a successful resolution of ...

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard. Their rampant use ...