A major regulator of neutrophil production and survival is the cytokine granulocyte colony-stimulating factor (G-CSF). Treatment with G-CSF can exacerbate underlying inflammatory diseases in ...

The four colony-stimulating factors (CSFs ... granulocytes and macrophages. Recombinant granulocyte-CSF (G-CSF) and granulocyte–macrophage-CSF (GM-CSF) have now been used to increase dangerously ...

This is the first regulatory approval of an inhaled recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) product for this indication. In Japan, Leukine is branded as Sargmalin and ...

This inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) is presently in Phase 3 development concerning autoimmune pulmonary alveolar proteinosis (aPAP). The drug is delivered via an ...