A major regulator of neutrophil production and survival is the cytokine granulocyte colony-stimulating factor (G-CSF). Treatment with G-CSF can exacerbate underlying inflammatory diseases in ...
The four colony-stimulating factors (CSFs ... granulocytes and macrophages. Recombinant granulocyte-CSF (G-CSF) and granulocyte–macrophage-CSF (GM-CSF) have now been used to increase dangerously ...
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Japan’s PMDA approves Partner’s inhaled Leukine for aPAPThis is the first regulatory approval of an inhaled recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) product for this indication. In Japan, Leukine is branded as Sargmalin and ...
Hosted on MSN11mon
Savara Inc. to Address Barclays Global Healthcare Conference on Rare Respiratory DiseasesThis inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) is presently in Phase 3 development concerning autoimmune pulmonary alveolar proteinosis (aPAP). The drug is delivered via an ...
Our lead program, MOLBREEVI*, is a recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar proteinosis (aPAP).
Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
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