Inhibitors of proximal and terminal complement cascades can often control red-cell hemolysis associated with paroxysmal nocturnal hemoglobinuria, but some patients have breakthrough hemolysis.

Furthermore, the rates of intravascular hemolysis, as measured by lactate dehydrogenase levels and hemoglobinuria, remain reduced in all patients, with 5 of 11 patients having been transfusion ...

To manage patients’ hemolysis, 68% (n = 13) underwent a dose increase of pegcetacoplan from twice weekly to 1080 mg every 3 days. This approach reportedly benefited 6 patients’ hemolytic outcomes.

Worldwide, millions of people suffer from hemolysis, the breakdown of red blood cells, such as those afflicted with sickle-cell disease, malaria or sepsis. These patients face an unprecedented ...

VUMC reports that while the usual signs of a brown recluse spider bite are painful, blistering skin lesions, these bites ...

Clinical use of the DAT. The DAT is useful in differentiating immune-mediated hemolysis from hemolysis caused by other factors ().It is important to note that a small but significant number of ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Researchers have discovered how hemolysis causes infections, and have found a new means to prevent it, paving the way to new treatment possibilities. Share: Facebook Twitter Pinterest LinkedIN Email.

Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury. World Journal of Gastroenterology, 2011; 17 (2): 213 DOI: 10.3748/wjg.v17.i2.213; ...

Hemolysis is not the only factor that should be considered when thinking about limiting PFA deliveries, she responded. “Because it’s fast and probably safe doesn’t mean that we should do extensive ...