Retention of vascular structures allowed for transplantation of recellularized liver graft in rats, and post-transplantation analysis demonstrated preservation of hepatocyte structure and function ...

Researchers reported here that they have pared down animal livers to their basic vascular structure and repopulated them with human liver progenitor and endothelial cells, taking a small step ...

“Whereas previous studies recellularized liver scaffolds largely with rodent hepatocytes, we repopulated not only the parenchyma with human iPSC-hepatocytes but also the vascular system with ...

Now we can incorporate cells found in different types of tissue around these interconnected vascular networks—such as hepatocytes from liver tissue and adipocytes from fat tissue—to study ...