The presence of intratumoural hypoxia is a negative prognostic indicator for many patients as it has been associated with increased local failure following radiotherapy and increased distant ...

Adenovirus-mediated overexpression of ORP150 in cultured primary cortical neurons suppressed hypoxia-induced apoptosis, and stroke volume was reduced in transgenic mice with targeted neuronal ...

When used in tandem with existing drugs, the implantable device shrunk mouse tumors by 90 percent, leading the study authors to suggest it could one day improve localized cancer treatments. Tumor ...

The immune protein STAT6 may be a driver of pulmonary hypertension in people with obstructive sleep apnea, a study in mice ...

We’ve been able to show in a proof of concept study that some of those types of drugs in preclinical mouse models can provide neuroprotection and even extend lifespan. In response to hypoxia ...