Membrane proteins are proteins found in cell membranes, either at the surface or on intracellular organelles. Integral membrane proteins such as receptors and ion channels span the membrane.

However, yeast two-hybrid assays cannot be used to analyze several important protein classes, such as integral membrane proteins or transcription factors. Here we demonstrate the ability of the ...

Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it ...

With 20+ years of experience focused on membrane proteins, viruses, and antibodies, Integral Molecular's technologies have been integrated into the drug discovery pipelines of over 600 biotech and ...

Engineered immune cells known as CAR-T cells are utilized in cancer treatment. Researchers at Uppsala University have recently identified that CAR molecules can be transferred from CAR-T cells to ...

Most of these processes are performed by proteins embedded within the cellular membrane. While some proteins only cross the membrane once, many do so several times, like a thread being woven into ...