Broccoli and broccoli sprouts have the highest amount of the isothiocyanates. "Our paper focuses on the anti-cancer activity of one of these compounds, called sulforaphane, or SFN," Azarenko added.

Synthesis of N-β-brominated alkenyl isothiocyanates via dehydrogenation of alkyl isothiocyanates. Journal: Chemical Communications Published: 2024-06-06 DOI: ...

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells Peer-Reviewed Publication. Georgetown University Medical Center. Denver, Colo. ...

This report describes the oxidative metabolism of isothiocyanates to isocyanates catalyzed by rat liver microsomes. Incubation of 2-naphthylisothiocyanate, microsomes, and NADPH yielded either N,N′-di ...

High-Pressure Processing of Broccoli Sprouts: Influence on Bioactivation of Glucosinolates to Isothiocyanates. Journal of Agricultural and Food Chemistry, 2017; DOI: 10.1021/acs.jafc.7b01380; ...

But for humans, eating isothiocyanates confers health benefits. Studies have shown them to have anti-cancer properties, and anti-neurodegenerative effects against diseases such as Alzheimer’s.

Isothiocyanates are the principal irritant constituents of the mustard oils found in many members of Brassicaceae (previously Cruciferae), the mustard family.

Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore ...

On the other hand, sulfur-containing compounds, such as isothiocyanates and polysulfides, which are found in many vegetables, are known to promote geometrical isomerization of carotenoids (e.g ...