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生物通
2月
新型生物转化预处理技术提升体外碘摄取抑制评估 ...
为解决环境中甲状腺激素(TH)系统干扰化学物质(THSDCs)的快速筛查难题,研究人员通过整合外源性生物转化系统(BTS)优化体外钠碘同向转运体(NIS)抑制检测方法。研究建立了稳定转染人NIS的HEK293T细胞模型及大鼠FRTL-5细胞模型,采用Sandell-Kolthoff(SK)比色法替代传统放射性检测,成功评估23种模型化合物的 ...
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