A more recent approach is transplantation of mature liver cells, known as hepatocytes. “The problem is obtaining sufficient quantities of fully functioning hepatocytes,” says Ochiya.

CSP creates a favourable environment that facilitates the growth and development of the parasite in liver hepatocytes... Malaria infection is initiated by the injection of Plasmodium sporozoites ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

Liver hepatocyte organoids derived from normal (left) or mutant (right) mice showing accumulation of lipids (in green). Higher levels of lipids accumulate as big droplets inside each cell (nuclei ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...

Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...

A research team led by the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences, in ...

Could you start by giving us an overview of the new CellDrop app and its significance in the realm of hepatocyte analysis? The Hepatocyte app on the latest version of CellDrop software is the ...

The Rice lab of bioengineer Gang Bao and collaborators at Baylor College of Medicine have developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the ...

as cell membrane stabilisers and permeability regulators that prevent hepatotoxic agents from entering hepatocytes; (iii) as promoters of ribosomal RNAsynthesis, stimulating liver regeneration ...