资讯
MC-LR暴露诱导肝细胞生长抑制并增加RNA m6A甲基化 实验显示MC-LR以剂量依赖性方式降低肝细胞存活率和集落形成能力,同时肝组织和细胞中m 6 A水平显著升高,而其他器官无此变化,提示肝脏特异性表观调控。
为探究 [D-Leu1] MC-LR 和 MC-LR 对大鼠不同脑区的影响及氧化应激变化,研究人员用含这两种毒素的混合物处理大鼠,测定脑区毒素浓度、氧化应激指标等。结果显示毒素分布和氧化应激反应呈剂量和区域依赖性,为评估微囊藻毒素神经毒性提供依据。
本研究进一步获得了Sphingopyxis sp. YF1降解MC-LR和Adda的转录组和代谢组学数据,面阐明了生物彻底降解MC-LR及Adda的新途径和分子机制,为微生物在藻 ...
相关成果以“Biodegradation of MC-LR and its key bioactive moiety Adda by Sphingopyxis sp. YF1: Comprehensive elucidation of the mechanisms and pathways”(鞘氨醇盒菌YF1降解藻毒素 ...
To develop this type of tobacco, Drake and colleagues genetically altered a tobacco plant to produce an antibody to MC-LR, by inserting genes which code for the production of this antibody.
A guideline of 1 µg/ has been set by the World Health Organization (WHO) in order to regulate MC-LR, which is a marker for cyanobaterias, in drinking water. This work illustrates an LC-MS/MS technique ...
Water treatment plants—even in developed countries—can't always remove MC-LR completely, nor can they test for it often enough, said Nicholas Kotov, a professor in the departments of Chemical ...
When we think of promotional products and gifts, we don't tend to connect them with high design; the consumer world has a reputation for mass-production and crowd-pleasing that sets it aside. However, ...
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