Researchers have shown that lysosomes, key organelles for maintaining cellular stability, can be repaired once damaged by a process termed microautophagy. They identified molecules called STK38 and ...

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes - critically important ...

本研究针对植物树脂分泌腺体发育过程中自噬(autophagy)的时空特征与分子机制这一科学空白，通过整合透射电镜(TEM)、免疫金标记和共聚焦免疫荧光技术，系统解析了矮腰果树脂分泌周期中两种自噬类型（巨自噬macroautophagy和微自噬microautophagy）的阶段性分布规律。

Overview: Lysosomes are repaired by ESCRT-driven microautophagy, and STK38 and GABARAPs are key regulators of this process by recruiting ESCRTs to lysosomes. These regulators are essential to maintain ...

Osaka, Japan – Macrophages are part of the immune system’s frontline; they attack and eat invaders to protect surrounding cells. They, along with other cells, maintain intracellular conditions through ...