In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...

Using Alzheimer’s mouse models, human cells, and human brain tissue, the researchers demonstrated that lowering PU.1 promotes the expression of lymphoid immunoregulatory receptor proteins on microglia ...

Microglia (green) responding to aggregated beta-amyloid plaques (blue) in the mouse cortex. In Alzheimer’s disease, the leading cause of dementia, microglia—the brain’s immune defenders—can act as ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

The pandemic and its aftermath have raised anxiety to new levels. But the roots of anxiety-related conditions, including obsessive-compulsive spectrum disorder (OCSD), are still unclear. In a new ...

Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real ...

An international research team headed by scientists at the Salk Institute for Biological Sciences has developed an organoid model—a three-dimensional collection of cells that mimics features of human ...

Microglial cells, the primary immune cells of the brain and central nervous system, are known to undergo striking morphological changes in response to sensory or neural stimuli. However, the ...

Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...