尽管科学界已知线粒体应激信号（Mitochondrial Stress Signals）在调控寿命中扮演重要角色，但这些来自细胞能量工厂的信号，究竟是否直接参与了对细胞核“城墙”的保卫及其背后的机制一直未被阐明。 田烨团队以秀丽隐杆线虫为模型，利用遗传学手段在发育阶段抑制线粒体电子传递链（ETC）活性。令研究人员惊讶的是，这种早期的线粒体扰动虽然诱导了线粒体超氧阴离子（Superoxide）的产生 ...

Let’s start with a quick biology refresher: Mitochondria are the powerhouse of the cell. They convert the food we eat into ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most ...

Diabetic foot ulcers are slow-healing and increase the risk of infections and amputation. Researchers at Karolinska ...

The nuclear envelope (NE) is a dynamic and selective barrier that organizes genome function and nucleocytoplasmic ...

Mitochondrial diseases are severe, often untreatable, and they leave human cells unable to grow normally without outside help. A new study published in Nature Metabolism now shows that a single gene ...

Originally, the powerhouses of higher cells, the mitochondria, were independent organisms. Researchers have investigated to what extent their metabolism has blended with that of their host cells in ...

Researchers introduced a yeast enzyme, ScURA, into human cells, enabling nucleotide synthesis independent of mitochondrial ...

Robert F. Kennedy Jr.’s warning about mitochondria slipped in between the anti-vaccine junk science and the excoriation of pharmaceutical drugs as “the No. 3 killer in our country.” He was speaking in ...