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利用 CpG 负载突变体攻克大肠杆菌生产流感 NP 的细菌 RNA 安全难题
为解决大肠杆菌生产流感 NP 时细菌 RNA 带来的安全及一致性问题,华中农业大学的研究人员开展相关研究。他们发现 NP 结合细菌 RNA 增强免疫反应,且开发的 NP 突变体可解决安全问题。该成果为通用流感疫苗研发提供新方向,值得一读。
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