I do think that it will be a female superhero who fells the final fatal blow to that shrivelled up prune of a bad guy Thanos. But it might be someone other than Captain Marvel. It could be Nebula.

How is Thanos planning to conquer the entire universe? With one cosmic weapon: the Warlock’s Eye. The Warlock’s Eye grants its wielder unparalleled telepathic power on a universal scale ...

Narrator: The trailer starts out with the team deciding to go after Thanos to avenge their friends. We see the Benatar approaching New York, then Rocket and Nebula sitting on its steps.