This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...

Association studies provide genome-wide information about the genetic basis of complex disease, but medical research has focused primarily on protein-coding variants, owing to the difficulty of ...

Long noncoding RNAs (lncRNAs) could be a byproduct of transcription (i), a scaffold linking proteins (ii) or a guide bringing proteins to specified parts of the genome (iii).

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Myocardial hypertrophy is a condition characterized by thickening of the ventricular wall and commonly associated with progression to heart failure. It develops when the heart is subjected to ...

The most commonly recognized function of RNA is to code for proteins in the body, but 75% of the human genome generates noncoding RNA that does not code for proteins. A substantial portion of these ...

Noncoding RNAs as master regulators in brain. According to Debra Silver, a developmental neurobiologist at the Duke University School of Medicine in North Carolina, researchers have for nearly half a ...

PURPOSELong noncoding RNAs (lncRNAs) were recently implicated in modifying pyroptosis. Nonetheless, pyroptosis-related lncRNAs and their possible clinical relevance persist largely uninvestigated in ...

Definitions Box: Long noncoding RNAs (lncRNAs) are RNAs longer than 200 nucleotides that do not contain any open reading frames greater than 300 nucleotides (100 codons). The DNA sequences they’re ...

Not junk, after all. Using CRISPR-Cas13 to edit RNA and avoid off-target activity, the researchers systematically profiled nearly 6,200 gene pairs of long noncoding RNAs (lncRNAs) and nearby ...

Noncoding DNA explains a majority of the heritability of dairy cattle traits, like milk production and fertility. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 ...