The determination in 1953 of the structure of deoxyribonucleic acid (DNA), with its two entwined helices and paired organic bases, was a tour de force in X-ray crystallography. But more ...

Nucleic acid-based techniques, such as polymerase chain reaction (PCR) and DNA sequencing, are widely used in molecular diagnostics. These methods allow for the detection and identification of ...

Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches. Our goal is to generate a better understanding of how ...

The structure of nucleic acid A nucleotide is made up of three parts that are attached by bonds. The three parts are a phosphate group, a 5-carbon sugar, and a nitrogen base.

Nucleic acid immunity involves a sophisticated set of mechanisms for identifying nucleic acids by immune receptors, playing a vital role in physiological ...

This article was originally published with the title “ Triple Helix: Designing a New Molecule of Life ” in Scientific American Magazine Vol. 299 No. 6 (December 2008) doi:10.1038 ...