Scientists share detailed, complete images of a viral structure called the Ebola virus nucleocapsid. This breakthrough may accelerate the development of antivirals that target this viral structure ...

核衣壳蛋白（Nucleocapsid，N蛋白）作为冠状病毒的主要结构蛋白之一，在新冠病毒的生命周期中起着至关重要的作用。它可以与病毒RNA形成核糖核蛋白 ...

Viral nucleocapsid protein is a potential antiviral drug target, serving multiple critical functions during the viral life cycle. However, the structural information of SARS-CoV-2 nucleocapsid ...

为解决SARS-CoV-2变异株逃逸现有疫苗保护的问题，研究人员通过免疫信息学(immunoinformatics)和反向疫苗学(reverse vaccinology)技术，设计了一种靶向刺突蛋白(spike)和核衣壳蛋白(nucleocapsid)的多表位mRNA疫苗。该疫苗覆盖99.99%全球人群，能 ...

The nucleocapsid’s cylindrical shape is made up of three layers; each layer plays a different role as the virus replicates in host cells. Before LJI’s imaging studies, ...

Preliminary scientific report. bioRxiv preprint server. 2020. Lutomski CA. Autoproteolytic Products of the SARS-CoV-2 Nucleocapsid Protein are Primed for Antibody Evasion and Virus Proliferation.

A coiling protein “shell,” called a nucleocapsid, shown here, surrounds Ebola’s genetic material, which consists of single-strand RNA. University of Delaware researchers are simulating the way ...

Inhibiting nucleocapsid phosphorylation impairs SARS-CoV-2's ability to replicate. getty. A cross-institutional effort between researchers at Weill Cornell Medicine and Duke University has yielded ...

Their findings reveal that nucleocapsid-based vaccines are effective in preventing SARS-CoV-2 infection in distal organs, such as the brain. Skip to content. Menu. Medical Home Life Sciences Home.

A recent manuscript demonstrates that single point mutations in the specific region of the Nucleocapsid (N) protein, position 199-205, substantially increase the infectivity of the virus, ...

The nucleocapsid (N) protein of severe acute respiratory syndrome-coronavirus (SARS-CoV) is a major virion structural protein. In this study, two epitopes (N1 and N2) of the N protein of SARS-CoV ...