Researchers used CRISPR gene editing to selectively kill cancer cells with amplified oncogenes. In animal and cellular models ...

In cellular and animal models of neuroblastoma, small cell lung cancer and colon cancer, this strategy reduces tumours, prolongs survival and triggers a tumour-fighting immune response. The study, ...

The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes ...

Lung cancer in never smokers is rising, with distinct risks and biology, highlighting the need for tailored screening, ...

Case Western Reserve University researchers have taken a dramatic step forward in the fight against cancer—all by starting at the very beginning. Scientists led by School of Medicine Professor Mark W.

Perioperative therapy has become a critical component in the management of resectable non–small cell lung cancer (NSCLC), particularly in the era of precision medicine. Although molecular testing is ...

“Our findings suggest that increase expression levels of Derlin1 and PSMD10 genes in HeLa cells by the EBV-EBNA1 might induce cancer cell survival and accelerates the development of cervical cancer ...

Experimental drugs that directly inhibit the NSD2 enzyme have shown potential as an effective strategy against hard-to-treat cancers, such as lung and pancreatic tumors driven by KRAS mutations. The ...

Pancreatic cancer is notoriously hard to treat, often resisting therapies that target its most common mutations. Researchers have now uncovered a hidden three-part loop that fuels tumor growth, ...