Many drugs work by targeting proteins. Biologic medicines showed that proteins can be made into therapies too—in some cases using proteins from the body. Juvena Therapeutics works with a type of ...

In the world of protein degradation, sometimes a spanner in the works isn’t an inconvenience but the desired result. Paris-based Enodia Therapeutics has launched out of France’s Pasteur Institute and ...

A study co-led by UCLA scientists has found targeting a protein called endocan and its related signaling pathway could be a ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc. New strategies for dealing with these ...

Cell adhesion molecules (CAMS), i.e., laminin-1 or N-cadhedrin Adhesion and attractant Allow cells to grow along the surfaces of other cells (such as using pioneering axons for subsequent axons) ...