Diagnosis Acromegaly and hyperprolactinemia caused by a mixed-cell adenoma, secreting growth hormone and prolactin. Management Trans-sphenoidal surgery followed by medical therapy with 20 mg ...

In 95% of cases, acromegaly is caused by excessive growth hormone secretion from a pituitary adenoma, and is rarely the result of secretion of growth-hormone-releasing hormone or growth hormone ...

Pituitary tumors are common intracranial neoplasms that can cause significant morbidity due to hormonal dysregulation and compression of surrounding structures. Despite advancements in surgical ...

Acromegaly is a rare, chronic endocrine disorder characterized by excessive secretion of growth hormone (GH), most commonly resulting from a benign pituitary adenoma.

Patients with Cushing disease have a much higher likelihood of developing venous thromboembolism than those with other ...

Causes of acromegaly may be due to pituitary tumors or non-pituitary tumors. Pituitary tumors. This is the cause of acromegaly in more than 95 percent of people with the condition.

Familial Isolated Pituitary Adenomas. Apart from familial acromegaly, few studies, none systematic in nature, had been published on other types of familial pituitary tumors unrelated to MEN-1 or CNC.

Patients with acromegaly make too much growth hormone, which causes them to grow disproportionately large bones, organs and tissues.

Crinetics shares PATHFNDR trial data showing oral Palsonify maintained hormone and symptom control in acromegaly patients ...

In patients who transitioned from injected SRLs to once-daily oral PALSONIFY, mean insulin-like growth factor 1 (IGF-1) levels remained stable with IGF-1 (mean ± SE) of 0.93 ± 0.22 at OLE baseline and ...

Having high insulin-like growth factor I levels over a longer duration increased risk for cancer among adults with acromegaly, but not for those with nonfunction pituitary adenoma, according to ...