Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a type of blood cancer that affects immune system cells. It most often affects the skin but can also involve bone marrow and other cell types.

The activation of plasmacytoid dendritic cells leads to local secretion of IFNα in the pancreatic islets. ... C. Innate cell crosstalk in T1DM. Nat Rev Endocrinol 9, 127 (2013) ...

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound ...

To find out how MKs develop (megakaryopoiesis), the lead authors - namely, Florian Gärtner, Hellen Ishikawa-Ankerhold, Susanne Stutte, and Wenwen Fu - studied the place where MKs originate: the ...

A patient with a rare, aggressive, blastic plasmacytoid dendritic-cell neoplasm had tumor cells overexpressing BCL2 and had a response with a durable remission to venetoclax, a BCL2 inhibitor.

Introduction. Since the early reference to plasmacytoid dendritic cells (pDCs) in the paracortical area of reactive lymph nodes in 1958 by Lennert and Remmele, [] an abundance of new information ...

Jodi Karnell and colleagues have developed a monoclonal antibody, VIB7734, that reduces symptom severity in people with cutaneous lupus by targeting and depleting plasmacytoid dendritic cells (pDC ...

IMGN632 is a CD123-targeting ADC in clinical development for hematological malignancies, including blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute myeloid leukemia (AML), ...

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells. Download PDF Copy; Reviewed. Ludwig-Maximilians-Universitaet Muenchen (LMU) Jul 18 2024.

Young Woman With Thymoma Metastatic to the Brain Controlled With Gross Total Resection and Stereotactic Radiosurgery, With a Subsequent Uncomplicated Pregnancy The Diagnosis in Oncology article by ...

Young Woman With Thymoma Metastatic to the Brain Controlled With Gross Total Resection and Stereotactic Radiosurgery, With a Subsequent Uncomplicated Pregnancy The Diagnosis in Oncology article by ...