资讯

本研究首次在加蓬入侵物种黑家鼠(Rattus rattus)中检测到啮齿类疟原虫Plasmodium yoelii,通过系统筛查527只农村地区捕获的啮齿动物,发现2例阳性样本(0.38%)。研究采用分子生物学技术结合系统发育分析,证实其与当地原生啮齿动物携带的虫株高度同源,挑战了'啮齿类疟原虫仅限原生宿主'的传统认知,为 ...
厦门大学生科院,美国国立卫生研究院的研究人员发表了题为“The Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence”的文章,利用CRISPR-Cas9技术,QTL定位等确定了PyHEUL对疟原虫致病性的重要作用,这将为药物或疟疾疫苗的开发提供新的靶点和思路。
Here we show that the tetraspanin CD81, a putative receptor for hepatitis C virus2, is required on hepatocytes for human Plasmodium falciparum and rodent Plasmodium yoelii sporozoite infectivity.
Mouse erythrocytes parasitized with Plasmodium berghei or Plasmodium yoelii were separated by ultracentrifugation using preformed isodensity gradients of the discontinuous type. Three fractions were ...
The researchers used two well-established non-lethal strains of mouse parasites called Plasmodium yoelii XNL and P. chabaudi AS, and determined that acute MHV68 infection can suppress the anti ...
QIAprep&amp Plasmodium Kit enables streamlined detection of five malaria-causing parasites for epidemiological research and surveillance. Novel QIAGEN assays support mixed-infection tracking, ...
Citation: Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, del Portillo HA (2011) Exosomes from Plasmodium yoelii-Infected Reticulocytes Protect Mice from Lethal Infections. PLoS ONE 6(10 ...